PRI 6(2) crc

نویسنده

  • SHANE PATMAN
چکیده

Background and Purpose: The present study aimed to evaluate the consistency with which physiotherapists apply manual hyperinflation to a test lung using the AirViva-2 or Mapleson-B resuscitation circuit, and their ability to modify the technique as pulmonary characteristics change. Method: A quasi-experimental, randomized, repeatedmeasures design was used to study 16 volunteer physiotherapists performing manual hyperinflation to a test lung simulating three clinical situations. Each subject applied manual hyperinflation to the test lung for each simulation three times in one day using the resuscitation circuit that they would normally use in their clinical practice. Eight subjects used the Air-Viva-2 circuit and eight used the Mapleson-B circuit. Measurements of tidal volume (V T ), peak airway pressure (P aw ) and fraction of delivered oxygen (FDO 2 ) were recorded during each testing period. Inflation rate and minute volume were calculated. Results: As compliance decreased and airway resistance increased, V T decreased and P aw increased. Of the eight subjects using the Air-Viva-2 circuit, only three subjects delivered greater than 0.80 FDO 2 . All subjects using the Mapleson-B circuit delivered greater than 0.85 FDO 2 . Conclusions: Subjects demonstrated good consistency in the application of manual hyperinflation for all three simulations and modified their technique appropriately as simulated pulmonary characteristics changed.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Pri-miR-124 rs531564 polymorphism and colorectal cancer risk

MiR-124 functions as a tumor suppressor and plays an important role in tumorigenesis. A common polymorphism (rs531564, C>G) in the pri-miR-124 has been recently studied in connection with cancer risk. The aim of the present study was to investigate the association between pri-miR-124 rs531564 polymorphism and the risk and clinicopathological characteristics of colorectal cancer (CRC). Two case-...

متن کامل

Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer.

The microRNA (miR)-34 family is a direct transcriptional target of tumor-suppressor TP53 and loss of miR-34 function may impair TP53-mediated cell cycle arrest and apoptosis. In the present study, we investigated whether the single nucleotide polymorphisms (SNPs) rs4938723 (T>C) in the promoter region of miR-34b/c and Arg72Pro (G>C) in codon 72 of TP53 are independently or complementarily assoc...

متن کامل

Head-to-head comparison of two online nomograms for prostate biopsy outcome prediction.

STUDY TYPE Diagnosis (exploratory cohort). LEVEL OF EVIDENCE 2b. What's known on the subject? and What does the study add? In recent years, several nomograms were developed in an effort to decrease the number of unnecessary prostate biopsies. The European SWOP-PRI and the North American PCPT are among the most popular. However, evidence on the relative predictive accuracy is lacking. A head-t...

متن کامل

Therapeutic strategies against cancer stem cells in human colorectal cancer

Colorectal cancer (CRC) is the third most frequent malignancy and represents the fourth most common cause of cancer-associated mortalities in the world. Despite many advances in the treatment of CRC, the 5-year survival rate of patients with CRC remains unsatisfactory due to tumor recurrence and metastases. Recently, cancer stem cells (CSCs), have been suggested to be responsible for the initia...

متن کامل

مطالعه تنوع ژنتیکی سویا (Glycine max) با استفاده از نشانگرهای ISSR

Recogniting the genetic diversity and classification of inheritancepools is one of important activities in the field of breeding and maintaining genetic resources in plants. In order to assess the genetic diversity in 48 genotypes of soybean amplification of gene loci was performed by using 10 ISSR primers In Genetics and Plant Breeding laboratory, College of Agriculture andNatural Resources, U...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002